Angelo M. Facchiano

This study develops capsaicin-derived ligands that modulate the AURKA/PHB2 interaction and mitophagy in cancer cells, with compound 13 showing promise as a specific inhibitor of AURKA-dependent mitophagy.

The paper identifies a mitochondrial gene orf125 linked to male sterility in potato hybrids and traces its evolutionary role in CMS development.

The paper analyzes how Omicron's spike mutations affect interactions with ACE2 and antibodies using 3D structures, predicting increased transmissibility and mixed antibody effects.

The paper identifies 746k polymorphic sites in Capsicum species and finds four novel loci associated with fruit shape, including a mutation in the Longifolia 1-like gene.