Author

Akishige Hokugo

University of California, Los AngelesORCID 0000-0002-7097-3364Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Akira KimotoiD· 1 shared Bryan J. McEntireiD· 1 shared Chika Nakanishi· 1 shared Daisuke TakedaiD· 1 shared Giuseppe PezzottiiD· 1 shared Ichiro NishimuraiD· 1 shared Junichi KikutaiD· 1 shared Karolina Elżbieta Kaczor‐UrbanowicziD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Akira KimotoORCID

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2 papers

Recent·Most cited

Single-cell RNA sequencing reveals collagen interactions between detached osteoclasts and activated fibroblasts in granulation tissue surrounding sequestra in medication-related osteonecrosis of the jaw

Chika Nakanishi, Takeshi Yoshida, Takuo Emoto, Yasumasa Kakei, Daisuke Takeda, Yujiro Hiraoka, Manabu Shigeoka, Akira Kimoto, Takumi Hasegawa, Akishige Hokugo, Tetsuya Hara, Yoshiaki Tadokoro, Noriaki Emoto, Junichi Kikuta, Tomoya Yamashita, Masaya Akashi

This study uses scRNA-seq to identify detached osteoclasts in MRONJ granulation tissue and reveals collagen-mediated interactions with fibroblasts.

bioRxiv · Feb 2, 2026 · PreprintImmunology

Silicon Nitride Induces Osteoconduction Via Activated Mitochondrial Oxidative Phosphorylation and Neovascularization

Wayne Gonzales, Ronit Khade, Takeru Kondo, Satomi Arimoto, Taro Inagaki, Akishige Hokugo, Karolina Elżbieta Kaczor‐Urbanowicz, Bryan J. McEntire, Ryan M. Bock, Takahiro Ogawa, Giuseppe Pezzotti, Ichiro Nishimura

This study shows that silicon nitride induces osteoconduction through mitochondrial oxidative phosphorylation and neovascularization in bone marrow mesenchymal stromal cells.

bioRxiv · Jul 9, 2024 · PreprintBioengineering