mitoSplitter: A mitochondrial variants-based method for efficient demultiplexing of pooled single-cell RNA-seq
Xinrui Lin, Yingwen Chen, Li Lin, Kun Yin, Rui Cheng, Xin Lin, Xiaoyu Wang, Ye Guo, Zhaorun Wu, Yingkun Zhang, Jin Li, Chaoyong James Yang, Jia Tao Song
mitoSplitter uses mitochondrial RNA variants to demultiplex pooled single-cell RNA-seq data, enabling efficient analysis of multiple samples without batch effects.
Proceedings of the National Academy of Sciences · Sep 19, 2023Peer-reviewedBioinformatics