Integrated analysis of cell-free DNA for the early detection of cancer in people with Li-Fraumeni Syndrome
Derek Wong, Ping Luo, Leslie E. Oldfield, Haifan Gong, Ledia Brunga, Ron Rabinowicz, Vallijah Subasri, Clarissa F. Chan, Tiana Downs, Kirsten M. Farncombe, Beatrice Luu, Maia Leigh Norman, Jenna Eagles, Stephenie Pederson, Johanna Wellum, , Trevor J. Pugh
This study evaluates an integrated liquid biopsy approach for early cancer detection in Li-Fraumeni syndrome patients, showing improved detection rates compared to individual methods.
medRxiv · Oct 7, 2022 · PreprintGenetic & Genomic Medicine