Vallijah Subasri

Multiomics unveils extracellular vesicle-driven mechanisms of endothelial communication in human carotid atherosclerosis

This study identifies EV-driven endothelial communication in human carotid atherosclerosis, showing increased angiogenic activity in symptomatic plaques.

tp53 R217H and R242H Mutant Zebrafish Exhibit Dysfunctional p53 Hallmarks and Recapitulate Li-Fraumeni Syndrome Phenotypes

This study characterizes zebrafish models of Li-Fraumeni syndrome with TP53 mutations, showing dysfunctional p53 pathways, tumor development, and mutation-specific phenotypes.

Integrated analysis of cell-free DNA for the early detection of cancer in people with Li-Fraumeni Syndrome

This study evaluates an integrated liquid biopsy approach for early cancer detection in Li-Fraumeni syndrome patients, showing improved detection rates compared to individual methods.