Author

Bernard Lam

Ontario Institute for Cancer ResearchORCID 0000-0002-6437-6491Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alexander T. BahcheliiD· 1 shared Andrea ArrudaiD· 1 shared Andrea M Bevan· 1 shared Arnavaz DaneshiD· 1 shared Beatrice LuuiD· 1 shared Clarissa F. ChaniD· 1 shared David M. MalkiniD· 1 shared Dax TortiiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Alexander T. BahcheliORCID

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2 papers

Recent·Most cited

Multi-platform reassessment of human mitochondrial DNA methylation reveals signals consistent with technical artifacts

Salman Basrai, Alexander T. Bahcheli, Djarren Tan, Philip C. Zuzarte, Andrea M Bevan, Theodore Chan, Kristie Ng, Bernard Lam, Andrea Arruda, Sunit Das, Mark David Minden, Jared T. Simpson, Jüri Reimand, Sagi Abelson

This study reassesses human mitochondrial DNA methylation using multiple platforms and finds signals likely due to technical artifacts rather than biological methylation.

bioRxiv · Jun 15, 2026 · PreprintBioinformatics

Integrated analysis of cell-free DNA for the early detection of cancer in people with Li-Fraumeni Syndrome

Derek Wong, Ping Luo, Leslie E. Oldfield, Haifan Gong, Ledia Brunga, Ron Rabinowicz, Vallijah Subasri, Clarissa F. Chan, Tiana Downs, Kirsten M. Farncombe, Beatrice Luu, Maia Leigh Norman, Jenna Eagles, Stephenie Pederson, Johanna Wellum, , Trevor J. Pugh

This study evaluates an integrated liquid biopsy approach for early cancer detection in Li-Fraumeni syndrome patients, showing improved detection rates compared to individual methods.

medRxiv · Oct 7, 2022 · PreprintGenetic & Genomic Medicine