Author

Joel G. Rurik

Karolinska InstitutetORCID 0000-0002-7156-4626Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Jonathan A. EpsteiniD· 2 shared Thomas WilliamsoniD· 2 shared Adi LightstoneiD· 1 shared Alekhya ParvathaneniiD· 1 shared Andrea L. BredemeyeriD· 1 shared Andrew L. KoenigiD· 1 shared Attila Kovacs· 1 shared Blake Jardin· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Jonathan A. EpsteinORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 21, 2026

Collateral Immune Cell Signaling Compromises the Efficacy of T-cell Engaging Therapies for Cardiac Fibrosis

Steven Hoseong Yang, Alekhya Parvathaneni, Yun-Ling Pai…·Kory J. Lavine

This study shows that FAP-targeted BiTE(R) molecules, intended to reduce cardiac fibrosis, instead worsen heart function by triggering harmful immune responses.

DOI 10.64898/2026.09.15.751626

mouseexperimental assay

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Cell BiologybioRxivPreprintFeb 25, 2025

In vivo anti-FAP CAR T therapy reduces fibrosis and restores liver homeostasis in metabolic dysfunction-associated steatohepatitis

Chittampalli N. Yashaswini, Bruno Cogliati, Tianyue Qin…·Scott L. Friedman

This study evaluates in vivo anti-FAP CAR T therapy for MASH, showing reduced fibrosis and restored liver homeostasis through HSC depletion and immune modulation.

13 citations

mousebulk RNA-seq

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