Author

Sisi Shan

Tsinghua UniversityORCID 0000-0002-7184-6818Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

Feng WUiD· 1 shared Fuli FengiD· 1 shared Jian PengiD· 1 shared Jianzhu MaiD· 1 shared Jing Wei· 1 shared Jun WuiD· 1 shared Linqi ZhangiD· 1 shared Ningguan Sun· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Feng WUORCID

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1 paper

Recent·Most cited

FlowDesign: Improved Design of Antibody CDRs Through Flow Matching and Better Prior Distributions

Jun Wu, Xiangzhe Kong, Ningguan Sun, Jing Wei, Sisi Shan, Fuli Feng, Feng WU, Jian Peng, Linqi Zhang, Yang Liu, Jianzhu Ma

FlowDesign improves antibody CDR design using flow matching and better priors, achieving higher affinity and neutralizing potency against HIV mutants.

Cell Systems · Apr 29, 2025Peer-reviewedBioinformatics