Fuli Feng

FoldAbS repurposes protein folding models as foundation encoders to improve antibody screening by evaluating specificity, affinity, and developability in a unified framework.

This paper benchmarks TCR-pMHC structure prediction tools using 70 unseen complexes and identifies the pLDDT score of the TCR CDR3 region as a key indicator of structural and functional accuracy.

Generanno is a genomic foundation model optimized for metagenomic annotation, achieving superior accuracy in coding region identification and enabling pseudogene prediction and taxonomic classification without reference databases.

FlowDesign improves antibody CDR design using flow matching and better priors, achieving higher affinity and neutralizing potency against HIV mutants.