Yasunori Sato

The paper evaluates experimental design in Perturb-seq, finding that correlated designs are robust in systems with signal amplification and introduces a metric to predict optimal designs.

The paper validates associations between combinations of dopaminergic gene polymorphisms and schizophrenia risk in a matched case-control study.

The paper identifies a genetic risk combination involving three SNPs related to dopaminergic signaling that predicts schizophrenia risk, despite individual SNPs not being significant on their own.