Kazuhiro Sakurada

BasalCell: A project scaffold generator for bioinformatics analysis

BasalCell provides a project scaffold generator to integrate R and Python ecosystems, enabling reproducible, multi-language bioinformatics workflows with version control and CI/CD.

Graph topology reframes the coherence of cell-state manifold inference under heterogeneous single-cell observations

The paper identifies how heterogeneous single-cell observations distort manifold-based inference and proposes topological stability descriptors to assess reliability.

Design-of-Experiments for Nonlinear, Multivariate Biology: Rethinking Experimental Design through Perturb-seq

The paper evaluates experimental design in Perturb-seq, finding that correlated designs are robust in systems with signal amplification and introduces a metric to predict optimal designs.