Benchmarking TCR-pMHC structure prediction: a unified evaluation and CDR3-based functional insights
J D Lu, Xinyuan Zhu, Xinting Hu, Cheng Zhang, Fuli Feng
This paper benchmarks TCR-pMHC structure prediction tools using 70 unseen complexes and identifies the pLDDT score of the TCR CDR3 region as a key indicator of structural and functional accuracy.
Briefings in Bioinformatics · May 1, 2026Peer-reviewedBioinformatics