Mechanisms of Cardiomyocyte Aging
Doğacan Yücel, Michael A. Trembley, Qingen Ke, Zexuan Wu, Peter M. Kang, William T. Pu
This study identifies molecular mechanisms of cardiomyocyte aging using single-nucleus RNA-seq, ATAC-seq, and epigenetic analyses in mice, revealing DNA methylation and ESRRG as key regulators.
bioRxiv · Jul 29, 2025 · PreprintMolecular Biology