Intranasal L-MYC Neural Stem Cells Restore Neurovascular and Neuroimmune Homeostasis After TBI via CX3CL1 Upregulation and ICAM-1 Downregulation
Brecken Enright, Jeffrey P. Cheng A. B, Vikram Adhikarla, Isabella Vasquez, Yate‐Ching Yuan, Corina O. Bondi, Russell C. Rockne, Anthony E. Kline, Margarita Gutova
This study shows that intranasal LMNSC01 treatment reduces neuroimmune and neurovascular dysfunction after TBI by modulating ICAM-1 and CX3CL1 expression in both male and female rats.
bioRxiv · Oct 12, 2026 · PreprintNeuroscience