Cancer BiologybioRxivPreprint
Cell-Cell Fusion in NSCLC Promotes Evolution of Therapeutic Resistance
Paulameena V. Shultes, Dagim Shiferaw Tadele, Arda Durmaz…·Jacob G. Scott
This study shows that cell-cell fusion in NSCLC leads to increased chemoresistance and tumor aggressiveness by creating hybrid cells with enhanced fitness and genomic heterogeneity.
DOI 10.1101/2024.12.02.626399