Synthetic BiologyProtein Engineering Design and SelectionPeer-reviewed
Engineering sensitivity and specificity of AraC-based biosensors responsive to triacetic acid lactone and orsellinic acid
Zhiqing Wang, Aarti Doshi, Ratul Chowdhury…·Patrick C. Cirino
This paper improves AraC-based biosensors for triacetic acid lactone and orsellinic acid by reducing background expression, enhancing sensitivity, and increasing specificity through dual-selection and computational methods.
15 citations