Rodrigo M. Maza

Context-dependent reconfiguration and spatial reorganisation of the miR-199a-5p/XIAP axis in high-grade serous ovarian cancer

This study examines the context-dependent relationship between miR-199a-5p and XIAP in cisplatin-sensitive and resistant ovarian cancer models and human tissue, revealing spatial reorganisation in resistant disease.

SpineDL: a Deep Learning-based approach for neuron andanatomical structure segmentation in immunofluorescenceimages of damaged spinal cords

SpineDL is a deep learning tool for segmenting neurons and anatomical structures in spinal cord immunofluorescence images, achieving expert-level performance.

Reanalysis of published data can help to characterize neuronal death after Spinal Cord Injury

The paper reanalyzes published spinal cord injury data to characterize neuronal death and evaluate neuroprotective effects using new methods and an open repository.

STEREOLOGICAL EVALUATION OF TISSUE PRESERVATION AFTERNEUROPROTECTIVE TREATMENTS FOR TRAUMATIC SPINAL CORDINJURY

The paper evaluates the use of stereological tools to assess tissue damage and neurodegeneration after spinal cord injury and tests the efficacy of different therapeutic strategies.

MiR-138-5p upregulation during neuronal maturation parallels with an increase in neuronal survival

This study shows that miR-138-5p upregulation during neuronal maturation reduces apoptosis and increases neuronal survival by modulating Caspase3 expression and activity.

MiR-182-5p regulates Nogo-A expression and promotes neurite outgrowth of hippocampal neurons in vitro

This study shows that miR-182-5p downregulates Nogo-A expression and promotes neurite outgrowth in hippocampal neurons, suggesting its potential as a therapeutic tool for CNS regeneration.