Manuel Nieto‐Díaz

This study examines the context-dependent relationship between miR-199a-5p and XIAP in cisplatin-sensitive and resistant ovarian cancer models and human tissue, revealing spatial reorganisation in resistant disease.

SpineDL is a deep learning tool for segmenting neurons and anatomical structures in spinal cord immunofluorescence images, achieving expert-level performance.

The paper shows that disease severity in a murine MS model correlates with oligodendrocyte production and that M-MDSCs are associated with increased oligodendrocyte generation.

The paper reanalyzes published spinal cord injury data to characterize neuronal death and evaluate neuroprotective effects using new methods and an open repository.

The paper evaluates the use of stereological tools to assess tissue damage and neurodegeneration after spinal cord injury and tests the efficacy of different therapeutic strategies.

This study shows that miR-138-5p upregulation during neuronal maturation reduces apoptosis and increases neuronal survival by modulating Caspase3 expression and activity.

This study shows that miR-182-5p downregulates Nogo-A expression and promotes neurite outgrowth in hippocampal neurons, suggesting its potential as a therapeutic tool for CNS regeneration.