Author

Pakhi Birla

Johns Hopkins UniversityORCID 0000-0002-7252-5717Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Cynthia L. SearsiD· 1 shared Drew M. PardolliD· 1 shared Franck HousseauiD· 1 shared Fyza Y. ShaikhiD· 1 shared Hadley E. Beauregard· 1 shared Haritha Padannapurath Manoj· 1 shared Hongni FaniD· 1 shared Kellie Nicole SmithiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Cynthia L. SearsORCID

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1 paper

Recent·Most cited

Synergistic role of riboflavin-auxotrophic Enterococcus for MR1 expression and intra-tumoral mucosal associated invariant T (MAIT) cell activation

Pakhi Birla, Lansaol Yang, W. Shan, Sukara Minamisawa, Omkar Dhaygude, Haritha Padannapurath Manoj, Ying Zheng, Hongni Fan, Hadley E. Beauregard, Kellie Nicole Smith, Fyza Y. Shaikh, Cynthia L. Sears, Drew M. Pardoll, Franck Housseau

The paper identifies riboflavin-auxotrophic Enterococcus spp. that synergize with metabolites to boost MR1 expression and activate MAIT cells in the tumor microenvironment.

bioRxiv · Nov 25, 2025 · PreprintImmunology