Author

Carlos A. Orozco

Instituto Nacional de CancerologíaORCID 0000-0002-7256-0942Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:proteomics· 1

Frequent Co-Authors

Alejandro Mejía García· 1 shared Alejandro Mejía‐GarcíaiD· 1 shared Boris Anghelo Rodriguez Rey· 1 shared Chen‐Yang SuiD· 1 shared Diego Alejandro Álvarez-DíaziD· 1 shared Geysson Javier FernándeziD· 1 shared Hsuan Megan TsaoiD· 1 shared Jean Jung· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Alejandro Mejía García

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintSep 28, 2026

Phenome-wide and proteomic analysis of APOE alleles across different ancestries in the All of Us Research Program

Alejandro Mejía García, Pablo Valderrama‐Carmona, Thomas M Zheng…·Sirui Zhou

This study identifies ancestry-specific APOE effects on phenotypes and plasma proteins in diverse populations, highlighting the need for ancestry-aware risk interpretation.

DOI 10.64898/2026.09.26.26364080

humanproteomics

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Cell BiologyPLoS ONEPeer-reviewedJul 31, 2026

Molecular Analysis and Computational Modeling Reveal Temporally Separable Responses triggered by DENV-Induced Soluble Factors in Endothelial Cells

Jenny Paola Alfaro-García, Julieta M Ramírez-Mejía, Paola Rojas-Estévez…·Miguel Vicente‐Manzanares

The paper investigates CMDV-induced changes in endothelial cells using molecular analysis and computational modeling, identifying key genes and pathways involved in endothelial dysfunction during severe Dengue.

DOI 10.1371/journal.pone.0354877

humanbulk RNA-seq

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Cancer BiologyPLoS ONEPeer-reviewedJul 24, 2026

Breast Cancer Clustering Integrating Complete Gene Expression Profiles and Genetic Ancestry

Johanna Stepanian, Alejandro Mejía‐García, Carlos A. Orozco, Jorge Duitama

This study integrates genetic ancestry and bulk RNA-seq data to subtype breast cancer, identifying three clusters with distinct biological and therapeutic characteristics.

DOI 10.1371/journal.pone.0352514

humanbulk RNA-seq

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