GeneticsbioRxivPreprint
Glycochenodeoxycholic acid and ceramide suppress the antiviral effect of 25-hydroxycholesterol against human norovirus infection in human intestinal enteroids
Wadzanai P. Mboko, Preeti Chhabra, Anna Maria Montmayeur…·Jan Vinjé
The paper shows that GCDCA and ceramide reduce the antiviral effect of 25-HC against norovirus in HIE, with 25-HC suppressing viral replication and altering gene expression related to cholesterol and interferon pathways.
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