Author

Ruijie Xu

St. Jude Children's Research HospitalORCID 0000-0003-3364-1587Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

Paul A. NorthcottiD· 2 shared Alexander AtamianiD· 1 shared Alexandra ScheuingiD· 1 shared Anna Maria MontmayeuriD· 1 shared David FilipoviciD· 1 shared Elizabeth J. ApsleyiD· 1 shared Esther B. E. BeckeriD· 1 shared Frederik ArnskötteriD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersDevelopmental Biology

Paul A. NorthcottORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintMar 25, 2026

Developmental determinants of male bias in medulloblastoma

Luca Bianchini, Ruijie Xu, David Filipovic…·Lena M. Kutscher

The paper investigates sex bias in medulloblastoma by analyzing multi-omics data and mouse models, finding that testosterone drives male predominance in this tumor.

DOI 10.64898/2026.03.25.714163

mousebulk RNA-seq

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NeuroscienceDisease Models & MechanismsPeer-reviewedFeb 1, 2024

PTCH1 mutant human cerebellar organoids are associated with altered neural development and early pathways of medulloblastoma oncogenesis

Max J. van Essen, Elizabeth J. Apsley, Joey Riepsaame…·Esther B. E. Becker

This study uses human iPSC-derived cerebellar organoids to investigate how PTCH1 mutations affect neural development and early medulloblastoma pathways.

32 citationstop 4%

humanexperimental assay

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GeneticsbioRxivPreprintJun 12, 2023

Glycochenodeoxycholic acid and ceramide suppress the antiviral effect of 25-hydroxycholesterol against human norovirus infection in human intestinal enteroids

Wadzanai P. Mboko, Preeti Chhabra, Anna Maria Montmayeur…·Jan Vinjé

The paper shows that GCDCA and ceramide reduce the antiviral effect of 25-HC against norovirus in HIE, with 25-HC suppressing viral replication and altering gene expression related to cholesterol and interferon pathways.

1 citation

humanbulk RNA-seq

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