Author

Mariel Kleer

University of CalgaryORCID 0000-0002-7277-3593Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Mariel Kleer1 paper · Dalhousie University

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1 Assay:proteomics· 1

Frequent Co-Authors

Jennifer A. CorcoraniD· 2 shared David C. SchriemeriD· 1 shared Julia Fox· 1 shared Maxwell P. Bui-MarinosiD· 1 shared Michael J.G. JohnstoniD· 1 shared Morgan F. Khan· 1 shared Rory P. MulloyiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

Jennifer A. CorcoranORCID

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2 papers

Recent·Most cited

Nuclear body assembly by a viral repeat RNA promotes Kaposi's sarcoma-associated herpesvirus gene expression

Mariel Kleer, Rory P. Mulloy, Maxwell P. Bui-Marinos, Michael J.G. Johnston, Morgan F. Khan, David C. Schriemer, Jennifer A. Corcoran

The paper shows that Kaposin, a viral lncRNA, remodels nuclear speckles to enhance KSHV gene expression by interacting with repetitive elements.

Molecular Cell · Sep 16, 2026Peer-reviewedMicrobiology

Kaposi's sarcoma-associated herpesvirus forms and maintains R-loops at origins of lytic replication

Mariel Kleer, Julia Fox, Jennifer A. Corcoran

This study investigates how KSHV maintains R-loops at replication origins by inhibiting RNaseH1, a key R-loop resolver, through RTA-mediated degradation.

bioRxiv · Sep 1, 2026 · PreprintMicrobiology