Author

Mari J. Aaltonen

McGill UniversityORCID 0000-0002-7333-9334Unclaimed ORCID profile · follow to get notified of new preprints

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:zebrafish· 1

Frequent Co-Authors

Alexandre JaneriD· 1 shared Christian J. Rampal· 1 shared Eric A. ShoubridgeiD· 1 shared Gary A.B. ArmstrongiD· 1 shared Lorne H. ZinmaniD· 1 shared Virginie Petel LégaréiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperDevelopmental Biology

Alexandre JanerORCID

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1 paper

Recent·Most cited

Loss of mitochondrial Chchd10 or Chchd2 in zebrafish leads to an ALS-like phenotype and Complex I deficiency independent of the mt-ISR

Virginie Petel Légaré, Christian J. Rampal, Mari J. Aaltonen, Alexandre Janer, Lorne H. Zinman, Eric A. Shoubridge, Gary A.B. Armstrong

This study shows that loss of Chchd10 or Chchd2 in zebrafish causes ALS-like symptoms and Complex I deficiency, with double KO showing more severe effects and mt-ISR activation.

bioRxiv · May 2, 2022 · PreprintDevelopmental Biology