The bidirectional causal effects of brain morphology across the life course and risk of Alzheimers disease: A cross-cohort comparison and Mendelian randomization meta-analysis
Roxanna Korologou‐Linden, Bing Xu, Elizabeth Jane Coulthard, Esther Walton, Alfie R. Wearn, Gibran Hemani, Tonya J.H. White, Charlotte A. M. Cecil, Tamsin H. Sharp, Henning W. Tiemeier, Tobias Banaschewski, Arun L.W. Bokde, Erin Burke Quinlan, Sylvane Desrivières, Herta Flor, , Emma Louise Anderson
This study uses Mendelian randomization to examine bidirectional causal effects between brain morphology and Alzheimer's disease risk across different life stages.
medRxiv · May 14, 2021 · PreprintGenetic & Genomic Medicine