Author

Edith Natalia Villegas Garcia

University of TriesteORCID 0000-0002-7338-2068Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:clustering· 2 Organism:human· 2 Assay:protein sequence· 2 Approach:Bayesian inference· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein design· 1

Frequent Co-Authors

Alessio AnsuiniiD· 2 shared Alberto CazzanigaiD· 1 shared Antonio Feltrin· 1 shared Arianna TasciottiiD· 1 shared Azad SadriD· 1 shared Daniele RamazzottiiD· 1 shared Davide Di Vora· 1 shared Elena BuscaroliiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

Alessio AnsuiniORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Learning Protein-Protein Interaction Interfaces from Multimodal Representations

Yuri Gardinazzi, Edith Natalia Villegas Garcia, Sergio Senci, Davide Di Vora, Antonio Feltrin, Francesca Cuturello

The paper develops ESM3-PPISites, a model that identifies protein-protein interaction interfaces using multimodal representations, outperforming existing methods and improving docking accuracy.

bioRxiv · Jun 9, 2026 · PreprintBioinformatics

BASCULE: Bayesian inference and clustering of mutational signatures leveraging biological priors

Elena Buscaroli, Azad Sadr, Riccardo Bergamin, Salvatore Milite, Edith Natalia Villegas Garcia, Arianna Tasciotti, Alessio Ansuini, Daniele Ramazzotti, Nicola Calonaci, Giulio Caravagna

BASCULE uses a Bayesian framework to standardize and cluster mutational signatures across cancer types, identifying prognostic subtypes in over 8,000 samples.

Genome biology · Dec 27, 2025Peer-reviewedCancer Biology

Protein family annotation for the Unified Human Gastrointestinal Proteome by DPCfam clustering

Federico Barone, Elena Tea Russo, Edith Natalia Villegas Garcia, Marco Punta, Stefano Cozzini, Alessio Ansuini, Alberto Cazzaniga

This paper annotates protein families in the Unified Human Gastrointestinal Proteome using DPCfam clustering, improving family coverage over Pfam.

Scientific Data · Jun 1, 2024Peer-reviewedBioinformatics