Nigel J. Emptage

Homeostatic regulation of presynaptic NMDA receptor subunit composition modulates action potential driven Ca2+ influx into boutons setting the bandwidth for information transfer

The paper identifies two presynaptic NMDAR subunit populations (GluN2A and GluN2B) and shows their distinct effects on Ca2+ influx and synaptic transmission bandwidth.

Heterosynaptic cross-talk of pre- and postsynaptic strengths along segments of dendrites

The paper investigates how pre- and postsynaptic strengths interact along dendritic segments, showing distance-dependent plasticity regulated by distinct signaling pathways.

Volumetric two-photon fluorescence imaging of live neurons using a multimode optical fiber

The paper describes a method for volumetric two-photon fluorescence imaging using a multimode optical fiber with a single transmission matrix measurement, demonstrating imaging of neurons in live rat brain slices.

Compact and contactless reflectance confocal microscope for neurosurgery

This paper introduces a compact reflectance confocal microscope for neurosurgery with high spatial resolution and potential for label-free, contactless use.

Minimally invasive deep-brain imaging through a 50 μm-core multimode fibre.

This paper introduces a holographic imaging technique through a 50 μm-core multimode fibre to achieve high-resolution deep-brain imaging with minimal tissue damage in living mice.

Glutamate release is inhibitory and unnecessary for the long-term potentiation of presynaptic function

The paper shows that glutamate release inhibits presynaptic function and is not required for long-term potentiation, with postsynaptic depolarization and nitric oxide release driving synaptic strengthening.