Different effects of 3-week disuse on the phenotype and gene expression of the calf and thigh muscles
Mira A. Orlova, Nadia S. Kurochkina, R. Yu. Zhedyaev, Nikita E. Vavilov, Viktor G. Zgoda, А. A. Puchkova, Anna A. Borzykh, Tatiana F. Vepkhvadze, Egor M. Lednev, Pavel A. Makhnovskii, Gleb V. Galkin, Valery E. Novikov, Alexey V. Shpakov, Попов Даниил Викторович
This study examines how 3-week disuse affects calf and thigh muscle phenotype and gene expression, finding greater declines in calf muscles with specific proteomic and transcriptomic changes.
The Journal of Physiology · May 11, 2026Peer-reviewedPhysiology