UNRAVELLING A HIDDEN SUBTYPE: MULTIOMICS REVEAL PSORIASIS-LIKE SIGNATURE WITH SURGICAL RELEVANCE IN A SUBSET OF PERIANAL FISTULIZING CROHN'S DISEASE
Saeed Abdurahiman, João Sabino, Sare Verstockt, Kristin Johnson, Lorenzo Giorio, Kaline Arnauts, Caitlin Van de Perre, Clara Caenepeel, Matthias Lenfant, Marc Ferrante, Tom Hillary, Anna-Teresa D’Hooghe, Gert D. Hertogh, Manon E. Wildenberg, Christianne Johanna Buskens, , Bram Verstockt
This study identifies molecular subtypes of perianal fistulizing Crohn's disease using multiomics, revealing a psoriasis-like keratinization signature linked to surgical outcomes.
bioRxiv · Jul 26, 2026 · PreprintImmunology