Author

João Sabino

Universitair Ziekenhuis LeuvenORCID 0000-0002-8892-7075Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1

Frequent Co-Authors

Bram VerstocktiD· 2 shared Kaline ArnautsiD· 2 shared Marc FerranteiD· 2 shared Saeed AbdurahimaniD· 2 shared Sare VerstocktiD· 2 shared Séverine VermeireiD· 2 shared André D’HooreiD· 1 shared Anna-Teresa D’HoogheiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersImmunology

Bram VerstocktORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 26, 2026

UNRAVELLING A HIDDEN SUBTYPE: MULTIOMICS REVEAL PSORIASIS-LIKE SIGNATURE WITH SURGICAL RELEVANCE IN A SUBSET OF PERIANAL FISTULIZING CROHN'S DISEASE

Saeed Abdurahiman, João Sabino, Sare Verstockt…·Bram Verstockt

This study identifies molecular subtypes of perianal fistulizing Crohn's disease using multiomics, revealing a psoriasis-like keratinization signature linked to surgical outcomes.

DOI 10.64898/2026.07.25.740704

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsJournal of Crohn s and ColitisPeer-reviewedSep 5, 2020

Intestinal receptor of SARS-CoV-2 in inflamed IBD tissue is downregulated by HNF4A in ileum and upregulated by interferon regulating factors in colon

Bram Verstockt, Sare Verstockt, Saeed Abdurahiman…·Séverine Vermeire

The paper investigates how intestinal inflammation in IBD affects SARS-CoV-2 entry receptors like ACE2, finding opposing regulation in ileum and colon.

51 citationstop 3%

humanbulk RNA-seq

𝕏 PostBluesky