BiochemistrybioRxivPreprint
ACKR3-arrestin2/3 complexes reveal molecular consequences of GRK-dependent barcoding
Qiuyan Chen, Christopher T. Schafer, Somnath Mukherjee…·John J. G. Tesmer
This paper reports cryo-EM structures of ACKR3-arrestin2/3 complexes phosphorylated by GRK2 or GRK5, revealing how phosphorylation barcodes influence arrestin binding modes and receptor configuration.
28 citations