Author

Alberto Bartesaghi

Duke UniversityORCID 0000-0002-7360-1523Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Andrew B. WestiD· 2 shared Arpine SokratianiD· 2 shared Elizabeth G. ViveretteiD· 2 shared Enquan XuiD· 2 shared Mario Juan BorgniaiD· 2 shared Ye ZhouiD· 2 shared Yuan YuaniD· 2 shared Addison M. DudaiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersNeuroscience

Andrew B. WestORCID

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2 papers

Recent·Most cited

NeuroscienceScience AdvancesPeer-reviewedNov 1, 2024

Mouse α-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases

Arpine Sokratian, Ye Zhou, Meltem Tatlı…·Andrew B. West

This study reports the atomic structure of mouse α-synuclein fibrils and shows they differ structurally and functionally from human fibrils linked to Parkinson's and MSA.

32 citationstop 1%

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 13, 2022

Structural and functional landscape of α-synuclein fibril conformations amplified from cerebrospinal fluid

Arpine Sokratian, Ye Zhou, Enquan Xu…·Andrew B. West

The paper identifies six novel α-synuclein fibril assemblies from cerebrospinal fluid samples and shows they have distinct functional properties despite no single structural feature predicting their function.

11 citations

humanprotein structure

𝕏 PostBluesky