Author

Jose Andres Alepuz Guillen

Boston UniversityORCID 0000-0002-7366-3484Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

David A. HarrisiD· 1 shared Janelle S. Vultaggio· 1 shared Jean R.P. GatdulaiD· 1 shared Robert C.C. MerceriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperNeuroscience

David A. HarrisORCID

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1 paper

Recent·Most cited

Membrane-anchored PrPSc is the trigger for prion synaptotoxicity

Jean R.P. Gatdula, Robert C.C. Mercer, Jose Andres Alepuz Guillen, Janelle S. Vultaggio, David A. Harris

This paper investigates the role of membrane-anchored PrPSc in prion-induced synaptotoxicity and shows that preventing its formation reduces synaptic damage.

PLoS Pathogens · Jan 28, 2026Peer-reviewedNeuroscience