A rare human TNFAIP3 variant reveals how A20 abundance is regulated by TAX1BP1
Cindy Eunhee Lee, Morgan B. Downes, Rochna Chand, Keisuke Horikawa, Vicki Athanasopoulos, Bahar Miraghazadeh, Matthew Cook
The paper identifies a rare TNFAIP3 variant that shows A20 phosphorylation regulates its abundance via autophagy, not MALT1 degradation, through an interaction with TAX1BP1.
bioRxiv · Mar 26, 2026 · PreprintImmunology