Author

Hiroyuki Honda

Nagoya UniversityORCID 0000-0002-7411-812XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Hirokazu AkiyamaiD· 2 shared Kazunori ShimizuiD· 2 shared Rin Kobayashi· 1 shared Shunnosuke Nakamura· 1 shared Takao YasuiiD· 1 shared Yosuke Katayama· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersBioengineering

Hirokazu AkiyamaORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintSep 30, 2026

Engineering robust cardiomyocyte differentiation from iPSCs through WNT-mediated process window expansion

Hirokazu Akiyama, Rin Kobayashi, Shunnosuke Nakamura…·Hiroyuki Honda

This study shows that early WNT inhibition expands the process window for robust cardiomyocyte differentiation from hiPSCs, improving efficiency and reducing variability.

DOI 10.64898/2026.09.29.755404

humanexperimental assay

𝕏 PostBluesky

BioengineeringStem Cell Research & TherapyPeer-reviewedJun 2, 2025

Engineering a Controlled Cardiac Multilineage Co-Differentiation Process Using Statistical Design of Experiments

Hirokazu Akiyama, Yosuke Katayama, Kazunori Shimizu, Hiroyuki Honda

This study engineers a controlled cardiac multilineage co-differentiation process using statistical design of experiments to generate cardiomyocytes, mural cells, and endothelial cells from iPSCs with high controllability and maturity.

DOI 10.1186/s13287-025-04408-0

humanstatistical model

𝕏 PostBluesky