Molecular BiologybioRxivPreprint
The opposing mechanisms by which miRNAs critically contribute to differential roles of Nrf1 and Nrf2 in modulating the epithelial-mesenchymal transformation of hepatocellular carcinoma
Juan Chen, Jing Qi Feng, Yuping Zhu…·Yiguo Zhang
This study identifies how Nrf1 and Nrf2 regulate miRNAs to differentially modulate EMT in hepatocellular carcinoma cells, with Nrf1 inhibiting and Nrf2 promoting EMT through distinct miRNA pathways.
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