Author

Yuping Zhu

Chongqing UniversityORCID 0000-0002-1192-6197Unclaimed ORCID profile · follow to get notified of new preprints

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Yuping Zhu2 papers · Chinese Academy of Sciences

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Yiguo ZhangiD· 3 shared Lu QiuiD· 2 shared Shaofan HuiD· 2 shared Jing Qi FengiD· 1 shared Juan CheniD· 1 shared Meng WangiD· 1 shared Xufang RuiD· 1 shared Yuancai XiangiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMolecular Biology

Yiguo ZhangORCID

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3 papers

Recent·Most cited

The opposing mechanisms by which miRNAs critically contribute to differential roles of Nrf1 and Nrf2 in modulating the epithelial-mesenchymal transformation of hepatocellular carcinoma

Juan Chen, Jing Qi Feng, Yuping Zhu, Shaofan Hu, Yiguo Zhang

This study identifies how Nrf1 and Nrf2 regulate miRNAs to differentially modulate EMT in hepatocellular carcinoma cells, with Nrf1 inhibiting and Nrf2 promoting EMT through distinct miRNA pathways.

bioRxiv · Nov 30, 2024 · PreprintMolecular Biology

A unity of opposites in between Nrf1- and Nrf2-mediated responses to the endoplasmic reticulum stressor tunicamycin

Yuping Zhu, Shaofan Hu, Xufang Ru, Ze Zheng, Zhuo Fan, Lu Qiu, Yiguo Zhang

This paper investigates the opposing yet coordinated roles of Nrf1 and Nrf2 in response to tunicamycin-induced ER stress, showing how they regulate gene expression and maintain cellular homeostasis.

bioRxiv · May 31, 2019 · PreprintMolecular Biology

A naturally-occurring dominant-negative competitor of Keap1 against its inhibition of Nrf2

Lu Qiu, Meng Wang, Yuping Zhu, Yuancai Xiang, Yiguo Zhang

The paper identifies a naturally-occurring Keap1 mutant, Keap1{Delta}C, that acts as a dominant-negative competitor, reducing Keap1's ability to inhibit Nrf2 and thereby increasing Nrf2-target gene expression.

International Journal of Molecular Sciences · Jul 24, 2018Peer-reviewedMolecular Biology