Identifying the therapeutic potential of Niclosamide in overcoming IFN-gamma dependent cancer immune evasion in the Tumor Microenvironment
Y. Zhang, Sophia Peng, Hamid Akhbariyoon, Suzi Kim, Ellie Lai, En Cai
This study identifies Niclosamide as a dual STAT1/STAT3 inhibitor that suppresses PD-L1 expression, reduces cancer stemness, and enhances T cell function in the tumor microenvironment.
Frontiers in Immunology · Mar 16, 2026Peer-reviewedImmunology