From Space to Sequence and Back Again: Iterative DNA Proximity Ligation and its Applications to DNA-Based Imaging
Alexander A. Boulgakov, Erhu Xiong, Sanchita Bhadra, Andrew D. Ellington, Edward M. Marcotte
This paper introduces iterative proximity ligation (IPL) to capture spatial information through DNA sequencing and demonstrates its ability to reconstruct spatial patterns from sequence data.
bioRxiv · Nov 14, 2018 · PreprintBioinformatics