Sanchita Bhadra

This paper introduces a computational pipeline using DNA k-mer imprints to agnostically classify and distinguish materials based on their sequence patterns.

The paper introduces a rapid, semi-quantitative LAMP-OSD test for detecting Enterococci in water, enabling visual readout and comparison with contamination standards.

The paper develops a RT-qPCR assay using a thermostable reverse transcriptase/DNA polymerase (RTX) and provides protocols for reagent production, aiming to improve testing scalability and reliability in resource-limited settings.

The paper demonstrates that Taq DNA polymerase can be optimized for reverse transcriptase activity, enabling its use as the sole enzyme in TaqMan RT-qPCR assays for detecting SARS-CoV-2 RNA.

The paper converts existing SARS-CoV-2 LAMP assays to use sequence-specific fluorogenic probes, improving specificity and demonstrating detection in human saliva.

This paper introduces iterative proximity ligation (IPL) to capture spatial information through DNA sequencing and demonstrates its ability to reconstruct spatial patterns from sequence data.

This paper develops a multiplex isothermal diagnostic assay for detecting variable viral targets, demonstrating its effectiveness against divergent Zika virus lineages.

This paper develops a LAMP-OSD assay with cellphone imaging for rapid, accurate detection of mosquito species and Wolbachia infection in field samples.