Author

Janine Kirby

University of SheffieldORCID 0000-0002-7468-5917Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Adrian Higginbottom· 1 shared Allan Christian ShawiD· 1 shared Chloé MoutiniD· 1 shared Cleide Dos Santos SouzaiD· 1 shared Gergo Erdi-KrausziD· 1 shared Guillaume M. HautbergueiD· 1 shared Iris-Stefania PasniceanuiD· 1 shared Johnathan Cooper‐KnockiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Adrian Higginbottom

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintJul 20, 2026

Astrocyte dysfunction distinguishes monozygotic twin C9orf72 expansion carriers discordant for amyotrophic lateral sclerosis.

Allan Christian Shaw, Iris-Stefania Pasniceanu, Rebecca Stevenson…·Pamela J. Shaw

This study identifies distinct astrocyte states in C9orf72 expansion carriers discordant for ALS, linking epigenetic changes, stress, and functional dysfunction to disease onset.

DOI 10.64898/2026.07.15.738192

humanDNA methylation

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