Programmed downregulation of METTL3 is essential for decidualization in both humans and mice
Yuqi Hong, Run-Fu Jiang, Shi Hui Tang, Xiaoqi Yang, Meng Zhang, Yi Liu, Qingyan Zhang, Chenhui Ding, Zhan‐Hong Zheng, Yanwen Xu, Shuhan Yang, Jilong Liu
This study shows that reducing METTL3 is necessary for decidualization in humans and mice by maintaining HAND2 expression through m6A modification.
The FASEB Journal · Dec 16, 2025Peer-reviewedPhysiology