Author

Pauline Poh Kim Aw

Agency for Science, Technology and ResearchORCID 0000-0002-7481-2824Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Balakrishnan Chakrapani NarmadaiD· 2 shared Collins Oduor OwinoiD· 2 shared Giridharan PeriyasamyiD· 2 shared Niranjan ShirgaonkariD· 2 shared Ramanuj DasGuptaiD· 2 shared Seng Gee LimiD· 2 shared Amy Yuh Ling Tay· 1 shared Atefeh KhakpooriD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Balakrishnan Chakrapani NarmadaORCID

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2 papers

Recent·Most cited

Identification of Cyclin L1 as a host factor regulating Hepatitis B Virus replication

Collins Oduor Owino, Balakrishnan Chakrapani Narmada, Gian Yi Lin, Pauline Poh Kim Aw, Nivrithi Ganesh, Jovi Tan Siying, Marie‐Laure Plissonnier, Matan Thangavelu Thangavelu, Niranjan Shirgaonkar, Pablo Juan Bifani, Massimo Levrero, Giridharan Periyasamy, Seng Gee Lim, Ramanuj DasGupta

This study identifies Cyclin L1 as a host factor that regulates Hepatitis B Virus replication by modulating RNA Polymerase II phosphorylation and activity.

Viruses · May 8, 2026Peer-reviewedMicrobiology

Single cell profiling of functionally cured Chronic Hepatitis B patients reveals the emergence of activated innate and an altered adaptive immune response in the intra-hepatic environment

Balakrishnan Chakrapani Narmada, Atefeh Khakpoor, Niranjan Shirgaonkar, Sriram Narayanan, Pauline Poh Kim Aw, Malay Singh, Kok Haur Ong, Collins Oduor Owino, Jane Wei Ting Ng, Hui-Chuing Yew, Nu Soibah Binte Mohamed Nasir, Veonice Bijin Au, Reina Sng, Nivashini Kaliaperumal, Htet Htet Toe Wai Khine, , Ramanuj DasGupta

The paper profiles single-cell transcriptomes of CHB and FC patients to identify immune cell states associated with functional cure.

bioRxiv · Apr 26, 2022 · PreprintGenomics