Prasad Abnave

Ongoing repair of migration-coupled DNA damage allows stem cells to reach wound sites

The paper shows that migrating stem cells in planarians experience DNA damage, which is repaired to allow migration to wound sites.

Conservation of epigenetic regulation by the MLL3/4 tumour suppressor in planarian pluripotent stem cells

This study shows that MLL3/4 tumour suppressor function in planarian stem cells is conserved across evolution, suggesting a conserved epigenetic regulatory program.

Epigenetic analyses of planarian stem cells demonstrate conservation of bivalent histone modifications in animal stem cells.

This study uses ChIP-seq to analyze histone modifications in planarian stem cells, finding bivalent promoters conserved across animal stem cells.

The Abrogation Of Condensin Function Provides Independent Evidence For Defining The Self-Renewing Population Of Pluripotent Stem Cells

The paper shows that condensin I is essential for planarian stem cell maintenance and that only sigma-neoblasts can self-renew.

Conservation of EMT transcription factor function in controlling pluripotent adult stem cell migration in vivo in planarians

The paper develops a method to study stem cell migration in planarians and shows that EMT transcription factors are required for migration to wound sites and migratory cell morphology.