Aziz A. Aboobaker

The paper identifies enhancer-like elements in planarian adult stem cells using epigenetic and expression data, and links them to regulatory networks involved in regeneration.

The paper introduces ACME, a cell fixation-dissociation method for single-cell transcriptomics that preserves RNA integrity and enables cryopreservation and sorting, validated with SPLiT-seq in planarians.

The paper shows that migrating stem cells in planarians experience DNA damage, which is repaired to allow migration to wound sites.

This study shows that MLL3/4 tumour suppressor function in planarian stem cells is conserved across evolution, suggesting a conserved epigenetic regulatory program.

This study uses ChIP-seq to analyze histone modifications in planarian stem cells, finding bivalent promoters conserved across animal stem cells.

The paper shows that condensin I is essential for planarian stem cell maintenance and that only sigma-neoblasts can self-renew.

The paper develops a method to study stem cell migration in planarians and shows that EMT transcription factors are required for migration to wound sites and migratory cell morphology.

The paper sequences and annotates the genome of Parhyale hawaiensis, identifying key genes for development, immunity, and lignocellulose digestion, providing a resource for comparative studies.