Generation of Vascularized Brain Organoids to Study Neurovascular Interactions
Xin-Yao Sun, Xiang-Chun Ju, Yang Li, Peng-Ming Zeng, Jian Wu, Yingying Zhou, Libing Shen, Jian Dong, Yuejun Chen, Zhen‐Ge Luo
Fusing stem cell-derived vessel organoids with cerebral organoids yields brain organoids containing vascular networks, BBB-like features and responsive microglia, with more neural progenitors than unfused controls.
eLife · May 4, 2022Peer-reviewedDevelopmental Biology✦ In-depth digest