Author

Jian Dong

ShanghaiTech UniversityORCID 0000-0002-0680-3969Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Zhen‐Ge LuoiD· 2 shared Dong-Dong Cao· 1 shared Jian Wu· 1 shared Libing SheniD· 1 shared Peng-Ming ZengiD· 1 shared Xiang-Chun JuiD· 1 shared Xiao-Yu Liao· 1 shared Xin-Yao Sun· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Zhen‐Ge LuoORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Hopx expression marks Aβ clearance astrocytes in Alzheimers disease

Dong-Dong Cao, Jian Dong, Xiao-Yu Liao, Yang-Yang Teng, Yang Gu, Zhen‐Ge Luo

This study identifies Hopx as a regulator of astrocytic function in Alzheimer's disease, showing that its expression is linked to Aβ clearance and reduced neurotoxic astrocyte generation.

bioRxiv · Feb 28, 2026 · PreprintNeuroscience

Generation of Vascularized Brain Organoids to Study Neurovascular Interactions

Xin-Yao Sun, Xiang-Chun Ju, Yang Li, Peng-Ming Zeng, Jian Wu, Yingying Zhou, Libing Shen, Jian Dong, Yuejun Chen, Zhen‐Ge Luo

Fusing stem cell-derived vessel organoids with cerebral organoids yields brain organoids containing vascular networks, BBB-like features and responsive microglia, with more neural progenitors than unfused controls.

eLife · May 4, 2022Peer-reviewedDevelopmental Biology✦ In-depth digest