Author

Tiago Tomazini Gonçalves

Universidade de São PauloORCID 0000-0002-7503-6062Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Luiz Osório LeiriaiD· 2 shared Marcelo Alves Silva MoriiD· 2 shared Adriana Leandra SantoroiD· 1 shared Andrei Carvalho SpositoiD· 1 shared Ariane Maria ZanescoiD· 1 shared C. Ronald KahniD· 1 shared Caio Fábio Baeta LopesiD· 1 shared Camila de Oliveira RamosiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPhysiology

Luiz Osório LeiriaORCID

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2 papers

Recent·Most cited

PhysiologyEMBO ReportsPeer-reviewedJun 22, 2026

E4BP4 Safeguards Brown Fat Mitochondria from Obesity-Induced Fragmentation via Ceramide Repression

Fernando Valdivieso Rivera, Vanessa de Oliveira Furino, Carlos Eduardo Pinheiro Leher…·Carlos H. Sponton

This study identifies E4BP4 as a transcriptional repressor that prevents obesity-induced mitochondrial fragmentation in brown fat by inhibiting ceramide synthesis, improving glucose homeostasis without weight loss.

DOI 10.1038/s44319-026-00826-0

mousebulk RNA-seq

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BiochemistrybioRxivPreprintMar 31, 2026

Cold acclimation reprograms hepatic lipid composition toward n-3 HUFAs to uncouple adipose-derived lipid flux from steatosis

Victor Azevêdo Vieira, Gabriel Salerno Costa, Gabriela Segura Gonzales…·Luiz Osório Leiria

The paper shows cold acclimation increases n-3 HUFAs in the liver, reducing steatosis by altering lipid composition and metabolism.

DOI 10.64898/2026.03.27.714471

mousemetabolomics

𝕏 PostBluesky