Sebastiaan Mastenbroek

This study compares blastocyst formation rates of human embryos cultured in media with varying pH and composition, finding similar rates between uterine-mimicking and standard media.

This study measures uterine temperature, pH, and fluid composition in humans three days after a positive LH test or ovum pick-up, finding lower pH and specific metabolite concentrations compared to in vitro culture conditions.

The paper shows high-quality human embryos secrete miR-320a, which promotes endometrial stromal cell migration, suggesting miR-320a could improve IVF success.