Author

Xinyu Cheng

Brandeis UniversityORCID 0000-0002-7559-9658Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Assay:imaging· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Stephen D. Van HooseriD· 2 shared Aishwarya BhonsleiD· 1 shared Avraham A LepskyiD· 1 shared Berith Isaac· 1 shared Dandan GengiD· 1 shared Dapeng LiiD· 1 shared Derek L. WiseiD· 1 shared Emma Y. Gao· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersNeuroscience

Stephen D. Van HooserORCID

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3 papers

Recent·Most cited

A motif for domain-specific analysis applets that are easy to learn, reuse, test, and to compose into pipelines: application to vision science

Avraham A Lepsky, Madeline K Severson, Ruyang Wang, Xinyu Cheng, Ricardo L Rodriguez, Rui Gong, Stephen D. Van Hooser

The paper introduces a framework for creating reusable, well-documented analysis tools in vision science, demonstrating their use in published research.

bioRxiv · Apr 30, 2026 · PreprintNeuroscience

A molecularly defined brain circuit module for regulating the panic-like defensive state

Miao Zhao, Li Zhang, Zhenhua Chen, Shuangfeng Zhang, Xinyu Cheng, Meizhu Huang, Xiating Li, Huating Gu, Xuyan Guan, Dandan Geng, Yaning Li, Yiheng Tu, Zhiyong Xie, Fan Zhang, Huijie Ma, , Peng Cao

The paper identifies Cbln2-expressing neurons in the posterior hypothalamic nucleus as essential for inducing panic-like defensive state in mice.

Nature Communications · Jul 1, 2025Peer-reviewedNeuroscience

Prolonged activity-deprivation causes pre- and postsynaptic compensatory plasticity at neocortical excitatory synapses

Derek L. Wise, Yasmin Escobedo Lozoya, Vera Valakh, Berith Isaac, Emma Y. Gao, Samuel B. Greene, Aishwarya Bhonsle, Qian L. Lei, Xinyu Cheng, Stephen D. Van Hooser, Sacha B. Nelson

The paper investigates how prolonged activity deprivation in mouse cortical slices affects synaptic and cellular properties, finding increased synaptic strength and reduced synaptic density.

eNeuro · May 22, 2024Peer-reviewedNeuroscience